Friday, March 26, 2010

Summary VII

Final summary post. Hansma and his exercising mice verified an exercise effect on mice femurs as published in June 2009. That's where the research (to my knowledge) stops and so we commence with speculation. How is calcium produced, and after production, how is calcium layed down within the bone tissue? The Qs further break down:

what is calcification?
what causes calcification?
what role calcification in bone strength and FR?
is there an exercise effect.

Calcium is more the generic term referring to the mineral salts produced within the Type I bone collagen cells in the form of hydroxyapetite (HA) platelets that self arrange within the collagen fibril and commence simultaneously to coat the outer skin and form rings around each fibril. The research implies certain chemical/physical/genetic triggers that cause each fibril to secrete the platelets. Query whether perhaps the squeezing and rearranging of bone tissue from equine speed work might accelerate these triggering processes?

After "production" by the fibrils there is a construction effect which Planck notes is two-fold:
1. The HA platelets themselves are "shaped" primarily into hexagonal shapes, but precise size and shape varies, and again we query whether there might be an exercise effect on platelet size and shape.
2. The platelets that coat the outer surface also self arrange generally in the form of rings, but it seems the arrangement may vary from total randomness to well organized patterns.

In terms of exercise effect on this, my posts were at the point of figuring how exercise might affect or change the manner in which platelets are layed down or constructed, as well as whether exercise might accelerate the production process. Hypothetically I'd suggested grabbing a single fibril at one end and slinging it with great force 240 times to simulate the affect of a mile race. Might such force affect the production, construction, and arrangement of HA platelets. That's where I'd left it.

Training:
Thurs. 3/25: Will post ground condition photos when I figure how this new 5 megapixel phone camera works. Relate, we're beyond mud. Sunny Friday. Weekend storms expected. Went to farm last two days to train. Declined to wade to the mounting stand to get on the horse. Off. walk in splashy conditions Fri.

0 Comments:

Post a Comment

Subscribe to Post Comments [Atom]

<< Home