A Partial Answer
The present question involves the role of ossification in bone strengthening and FR, and whether the exercise regimen of the horse can influence this process. Does e.g. an "exercised" bone contain calcium in different quantities, densities, or quality, and, if so, what would be the cause?
Envelope please.
BUT, wait, there is a tad bit of research on this to unconver, and, free on the internet. RR stumbles upon this from the Department of Orthopedic Surgery, University of Utah. It seems that our surgeons have some interest "Spacial distribution of Osteocyte Lacunae Equine Radii: Considerations of Microdamage Detection and Metabolism"> Wow.
Unfortunately, I was unable to access the larger study, but due to this short excerpt from the study, coming soon on this very blog at least a partial answer to the questions proposed initially above.
The study will seem incomprehensible to the reader without some basic knowledge. Hence, the prior You Tube episodes on bone anatomy, and you may go back to them and take a look at what is an osteocyte, the subject of the study title!
These osteocytes permeate the bone tissue including the osteons. They are the remnants of the osteoblasts doing their work in bone construction, and part of this work certainly is the secretion
of calcium salts!
BUT, and here is why thus far I have only a partial answer, I am having trouble nailing down the exact source of the calcium salts. This takes us to the question of the precise manner in which the bone tissue is constructed by the osteoblasts.
Do the osteoblasts merely secrete calcium salts which then builds up as bone tissue, or do the osteoblasts merely lay down new bone collagen. Big difference. I am pretty sure that it is the latter, though I'm unable to find any confirmation. Let's go with what I think: osteoblasts lay down new bone collagen and it is this collagen which overtime secretes the calcium salts, essentially ossifying itself into the hard bone tissue. At some final point the bone collagen cell actually dies leaving behind the calcified matrix it has secreted. This remains until osteoclasts tear it down--an eternal never ending process in the skeleton. Exciting stuff!
It will be necessary to understand the above when I present the research article next post.
Training:
still raining. we are disappointed.
Envelope please.
BUT, wait, there is a tad bit of research on this to unconver, and, free on the internet. RR stumbles upon this from the Department of Orthopedic Surgery, University of Utah. It seems that our surgeons have some interest "Spacial distribution of Osteocyte Lacunae Equine Radii: Considerations of Microdamage Detection and Metabolism"> Wow.
Unfortunately, I was unable to access the larger study, but due to this short excerpt from the study, coming soon on this very blog at least a partial answer to the questions proposed initially above.
The study will seem incomprehensible to the reader without some basic knowledge. Hence, the prior You Tube episodes on bone anatomy, and you may go back to them and take a look at what is an osteocyte, the subject of the study title!
These osteocytes permeate the bone tissue including the osteons. They are the remnants of the osteoblasts doing their work in bone construction, and part of this work certainly is the secretion
of calcium salts!
BUT, and here is why thus far I have only a partial answer, I am having trouble nailing down the exact source of the calcium salts. This takes us to the question of the precise manner in which the bone tissue is constructed by the osteoblasts.
Do the osteoblasts merely secrete calcium salts which then builds up as bone tissue, or do the osteoblasts merely lay down new bone collagen. Big difference. I am pretty sure that it is the latter, though I'm unable to find any confirmation. Let's go with what I think: osteoblasts lay down new bone collagen and it is this collagen which overtime secretes the calcium salts, essentially ossifying itself into the hard bone tissue. At some final point the bone collagen cell actually dies leaving behind the calcified matrix it has secreted. This remains until osteoclasts tear it down--an eternal never ending process in the skeleton. Exciting stuff!
It will be necessary to understand the above when I present the research article next post.
Training:
still raining. we are disappointed.
posted by rather rapid at
9:24 PM
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