Monday, April 12, 2010

Break Through(?)

The epiphany occurs. Uncertain just when. Things (may) have come together, finally. What is happening post race in those very warm to the feel cannon bones? Maybe we're a little closer to understanding.

This requires some technical explanation with aid of a few oft repeated images. Way back when the effect of speed work on a crystal lattice (right) was conjectured as having a compressive effect whereby lines connected by the blue dots would at the location of the blue dots slide together for a distance of half a nano space. The image, for purposes of discussion, consists of one bone cell, the though being if all the bone cells in process of speed work contract ever so slightly the entire bone will be contracted into increased density post race. This contractive effect at the molecular level was thought to be temporary, and was followed by a bounce back effect over a few days that would restore microscope bone to it's original pre-race shape and position, unless followed within a certain time by a 2nd speed work--or so it was speculated.

Since those suppositions much new research info has been added. E.g. the idea that mineralized bone lattice resembles in any way the crystal lattice of the material "glass", which is represented by the image, above right, is obviously incorrect. The bone lattice at the nano level looks nothing at all like the crystal lattice.

Instead, our bone cells are Type I Bone Collage Fibrils as imaged by Hansma, below.
The blue dots are the HA mineral platelets, and instead of being connected by lines, they are inter spaced with water and organic material. Moreover, we discovered these fibrils self arrange in bundles, as represented by the image from Planck, below:
but, these fibril arrays, instead of the organization above may be in various diffuse patterns noted in the image from Planck below which is identified as "level 4".
If I could blow the above up a bit, the pink image at the lower right shows the spacing in nano terms. How this may appear in real life terms is shown in the image that follows, a Hansma blow up, presumably fairly live cortical bone from a cow. Notice the spacing between the fibrils!
The experiment involving the above is to question what occurs to this tissue as our horse motors down the track at speed, exerting 12,000 lbs/sq. inch of pressure on these molecules/bone cells, which is about three times the pressure exerted on the tibia of a human sprinter. And, please note that the present analysis involves a possible effect on calcification from this. I'd previously hypothesized an effect contractive effect (see above), and a "rearrangement" effect on organic bone glue proteins with both of said effects providing over time and upon reinforcement by subsequent speed work--an effect of density, buttressing and strengthening. Will get back to the calcification part, shortly.

How does this all come together into a reasonable conclusion?

The key could be, as I am considering, to understand the structure of fibril arrays, and the nano-distances involved.

First, please note that the distance between two adjacent fibrils in those banding arrays is infinitesimally small--2 nms nano distance- there is spacing between the fibrils albeit microscopically tiny in the extreme!!!

May we thus suppose that under pressure of 12,000 lbs./sq. inch and the heat which that generates these fibrils would be pressed together during the speed work so that perhaps there is zero distance between the fibrils after a sufficient number of strides, and that post race, due to this pressure and heat build up the fibrils have adhered together eliminating nano spacing between them??

Significance/ramifications, next post.

Training:
Sun. 4/10: Third dry day of the year. 10 min. riderless spurts. Farthest these last due to conditions is 20-25 yards. Tack was 10 min trot were we stop on the turn arounds. Trotting Big Rod--pure torture. He can gallop, though, and we're into that soon.

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