Monday, December 07, 2009

SW Research Institute

Second link, last post. I might have some fun with this one since the researchers were dealing with "osteocyte loads" on "mouse bones".("we will measure osteocyte deformation ex vivo in mice long bones due to...") But, for weather and personal reasons strike all humor here and present a straightforward summary of the link.

First, some definitions, for which there is too much overlap for my taste, but bother to read through them to appreciate some very fine distinctions between bone "quality" and bone "strength" and bone "fracture toughness".

In the study


Bone quality = 1. bone porosity and mirco architecture. 2. bone mineral and organic constituents (i.e. is there more collagen or more mineralization in the bone sample). 3. micro damage accumulation.). May we presume that bone of high quality lacks porosity, has some ideal (but unknown) collagen/mineralization mix, and minimum micro damage.


Bone strength, as opposed to bone quality, seems to refer to bone mineral density + bone quality. I'm thinking you add "mineral density" to quality. If you have both you have strong bone. How do you get "mineral density" is a different but extraordinarily important question.



Interestingly BMD (bone mineral density)according to this study seems to account for but 4% of fracture risk, and the remaining 96% are unexplained for their purposes. I propose to clear up some of these mysteries


Then "bone fracture toughness" seemingly (to them) an amalgam of everything: porosity, micro architecture, osteonal morphology, collagen integrity, and micro damage "all of which are measures of bone quality."


Of further interest besides the forgoing definitions, the piece introduces the concepts of osteocyte loading (with mechanical strain) and subsequent deformation, substrate stretching, fluid flow in and around the bone cells. They go as far as to quantify this by showing x amount of deformation with y amount of strain. The point being, there is an "effect" the implication being increased mineralization resulting from strain.

But, that's where the useful part ends. Next post will summarize the Max Planck article.

Training:
Sun. 12/6: Art was driven riderless intermittently with short spurts up to :15 sec/f. Rod Off.
Mon. 12/7: Riderless workout intermittently for 10 min. numerous faster spurts in :14 range for both.
Tues. 12/8 With bad weather blowing in. we continue fast work and get possibly the best riderless fast work in quite a while. Numerous 2f near full speed bursts for both.
Wed. 12/9: Off

0 Comments:

Post a Comment

Subscribe to Post Comments [Atom]

<< Home